This work has a unique historical and artistic significance.
The influence of the Portinari Altar, which was erected in Florence in 1478, was felt by many of the Florentine painters and is reflected in particular in the works of Ghirlandaio and Leonardo.
Three members of the Portinari family, Tommaso Portinari and his two sons Antonio and Pigello, are portrayed kneeling, their faces pale, sculptural and almost ghostlike.
Tommaso Portinari's wife, Maria Baroncelli, with her elder daughter Margherita are accompanied by Mary Magdalen and St Margaret.
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